Welcome to Neurospan, a biotech startup
developing novel therapeutics for Alzheimer's disease.

Pathological changes in Alzheimer's Disease begin with increased levels of amyloid-beta (Aβ), preceding the formation of hallmark amyloid plaques, tau tangles, and neuronal loss. Phosphoglycerate dehydrogenase (PHGDH) is a pivotal mediator that integrates diverse environmental stimuli associated with sporadic Alzheimer's disease, triggering the initiation of Aβ production. Cell, 2025.

AI accelerated the discovery and optimization of our lead compound.
As featured in the NVIDIA technical Blog, 2025.